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Procaine penicillin Uses, Side Effects & Warnings - Drugs

Jun 02, 2020 · Procaine penicillin is an antibiotic that fights bacteria in your body. Procaine penicillin is used to treat many different types of infections caused by bacteria, including syphilis (a sexually transmitted disease). Do not use this medication for any other …

Brand name: Wycillin

Procaine penicillin G | C29H38N4O6S - PubChem

Like all penicillins, procaine benzylpenicillin interferes with the synthesis of the bacterial cell wall peptidoglycan. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable. It is part of the penicillin and …

Penicillin G Procaine - FDA prescribing information, side ...

Apr 26, 1948 · Penicillin G Procaine is chemically designated as (2 S, 5 R, 6 R)-3,3-Dimethyl-7-oxo-6- (2-phenylacetamido)-4-thia-1-azabicyclo [3.2.0]heptane-2-carboxylic acid compound with 2- (diethylamino)ethyl p -aminobenzoate (1:1) monohydrate. Its molecular formula is C 16 H 18 N 2 O 4 S∙C 13 H 20 N 2 O 2 ∙H 2 O with a molecular weight of 588.72.

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Penicillin G procaine | C29H40N4O7S - PubChem

Penicillin G Procaine is the procaine salt form of penicillin G, a broad-spectrum, beta-lactam, naturally occurring penicillin antibiotic with antibacterial activity. Penicillin G binds to and inactivates the penicillin binding proteins (PBPs) located inside the bacterial cell wall.

Procaine Penicillin - an overview | ScienceDirect Topics

Procaine penicillin G is a poorly soluble salt that is slowly absorbed after IM injection. It is the most commonly used formulation of penicillin in horses. Benzathine penicillin G is a very insoluble salt that is used in long-acting penicillin preparations, which contain a 50:50 mixture of procaine penicillin G and benzathine penicillin G.

Procaine Penicillin (Wycillin) - Side Effects ...

Jun 23, 2020 · Procaine penicillin is an antibiotic that fights bacteria in your body. Procaine penicillin is used to treat many different types of infections caused by bacteria, including syphilis (a sexually ...

PENICILLIN G PROCAINE Dosage and Administration | Pfizer ...

Penicillin G procaine (aqueous) is for intramuscular injection only. Administer by DEEP. DOSAGE AND ADMINISTRATION Do not inject into or near an artery or nerve. Injection into or near a nerve may result in permanent neurologic damage (see WARNINGS ).

Penicillin G Procaine (Penicilling Procaine Injection ...

Nov 17, 2017 · Penicillin G procaine is chemically designated as (2S, 5R, 6R)-3,3-Dimethyl-7-oxo-6- (2-phenylacetamido)-4-thia-1- azabicyclo [3.2.0]heptane-2-carboxylic acid compound with 2- (diethylamino)ethyl p-aminobenzoate (1:1) monohydrate. Its molecular formula is C 16 H 18 N 2 O 4 S•C 13 H 20 N 2 O 2 •H 2 O with a molecular weight of 588.72.

Penicillin G procaine dosing, indications, interactions ...

Moderate/severe respiratory tracts infection caused by pneumococci (use aqueous penicillin G for acute stage of severe pneumonia, empyema, bacteremia, pericarditis, meningitis, peritonitis, or...

Procaine and Benzathine Penicillin | Medcrine

Procaine penicillin is made by a combination of procaine and benzylpenicillin. This is done in that one mole part of procaine is combined with one mole part of penicillin. This way the peak activity of penicillin is delayed but the duration of action is prolonged to at least twelve hours.

Penicillin G Benzathine and Penicillin G Procaine ...

May 26, 2021 · Penicillin G benzathine and penicillin G procaine injection is in a class of medications called penicillins. It works by killing bacteria that cause infections. Antibiotics such as penicillin G benzathine and penicillin G procaine injection will not work for colds, flu, or other viral infections.

Procaine Benzylpenicillin - an overview | ScienceDirect Topics

Procaine penicillin G in a single daily intramuscular dose of 50,000 units/kg produces mean serum values of 7 to 9μg/mL for up to 12 hours and 1.5μg/mL at 24 hours after the dose in infants younger than 1 week of age (see Table 37–3). 155 Because the concentrations decrease more rapidly in older neonates, only 0.4μg/mL is detected at 24 hours.

Procaine Penicillin G Shortage CDC

Apr 17, 2017 · Penicillin G procaine is one of the recommended treatments for congenital syphilis and an alternative treatment for both neurosyphilis (NS) and ocular syphilis (OS). Pfizer, the sole manufacturer of Penicillin G procaine in the United States, continues to experience a manufacturing delay of this products.

DailyMed - PENICILLIN G PROCAINE injection, suspension

Nov 25, 2019 · Penicillin G procaine is an equimolecular compound of procaine and penicillin G, administered intramuscularly as a suspension. It dissolves slowly at …

Procaine benzylpenicillin: Uses, Interactions, Mechanism ...

Identification

Penicillin G Procaine (penicillin G procaine) dose ...

Penicillin G procaine is contraindicated in any patient with a history of a procaine hypersensitivity reaction. Patients with a history of sensitivity can be given a test dose of procaine intradermally (0.1 ml of a 1—2% procaine solution); development of erythema, wheal, flare, or eruption indicates procaine sensitivity and penicillin G ...

procaine penicillin | Michigan Medicine

Procaine penicillin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while using procaine penicillin. Hormonal forms of contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings ...

Pharmacokinetics of penicillin G procaine versus ...

Plasma and urine penicillin G and procaine concentrations were measured by use of high-pressure liquid chromatography. Results: Median elimination phase half-lives of penicillin G were 24.7 and 12.9 hours, respectively, after administration of PGP and penicillin G potassium.

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Bicillin C-R (penicillin G benzathine and penicillin G ...

Penicillin G benzathine and penicillin G procaine have a low solubility and, thus, the drugs are slowly released from intramuscular injection sites. The drugs are hydrolyzed to penicillin G. This combination of hydrolysis and slow absorption results in blood serum levels much lower but

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DailyMed - PENICILLIN- penicillin g procaine injection ...

Jun 02, 2021 · Description: Penicillin Injectable is a suspension of penicillin G procaine in 100, 250, and 500 mL multiple dose vials. Each mL is designed to provide 300,000 units of penicillin G as procaine in a …

Penicillins | Treatment summary | BNFc content published ...

Benzathine benzylpenicillin or procaine benzylpenicillin are used in the treatment of syphilis. Phenoxymethylpenicillin (Penicillin V) has a similar antibacterial spectrum to benzylpenicillin sodium, but is less active. It is gastric acid-stable, so is suitable for oral administration.

Bicillin CR (Penicillin G Benzathine and Penicillin G ...

Sep 06, 2019 · Bicillin C-R (penicillin G benzathine and penicillin G procaine injectable suspension) is supplied in packages of 10 disposable syringes as follows: 2 mL size, containing 1,200,000 units per syringe (21 gauge, thin-wall 1 inch needle for pediatric use), NDC 60793-601-10.

Penicillins - Pharmacology - Veterinary Manual

The penicillins are among the earliest classes of antibacterial drugs. Penicillins are divided into subclasses based on chemical structure (eg, penicillins, monobactams, and carbapenems), spectrum (narrow, broad, or extended), source (natural, semisynthetic, or synthetic), and susceptibility to β-lactamase destruction.

Penicillin [Equine] – OSU VMC Antimicrobial Use Guidelines

Background

Penicillin G Benzathine And Penicillin G Procaine ...

Jun 23, 2020 · Penicillin G benzathine and penicillin G procaine is a combination slow-onset antibiotic that is used to treat many types of severe infections caused by bacteria, including strep infections ...

US20060058280A1 - Preparation of penicillin procaine ...

A process for preparing penicillin G procaine comprises the steps of introducing inactive ingredients into a first mixing tank and sterilising the mixture of inactive ingredients in the first mixing tank. A procaine hydrochloride is dissolved in a second mixing tank, and the contents of the second mixing tank are added to the first mixing tank through a sterile filter.

Author: Reddy A. Kal, Raul Zavala

Procaine penicillin G | CAS#:54-35-3 | Chemsrc

Feb 05, 2021 · Chemsrc provides Procaine penicillin G(CAS#:54-35-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Procaine penicillin …

Questions and Answers for Consumers on Penicillin G Procaine

Penicillin G procaine is an antibiotic that is given by injection into a muscle. It is approved to treat bacterial infections in many different parts of the body. It does not work to treat viral ...

Penicillin G Procaine Intramuscular: Uses, Side Effects ...

Find patient medical information for penicillin G procaine intramuscular on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

PENICILLIN G PROCAINE How Supplied/Storage and …

HOW SUPPLIED Penicillin G Procaine Injectable Suspension is supplied in packages of 10 syringes and ten 21 gauge, thin-wall 1-1/2 inch needles as follows: 1 mL size, containing 600,000 units per syringe (21 gauge, thin-wall 1-1/2 inch needle), NDC 60793-

Penicillin G Procaine | Sigma-Aldrich

Synonym: Penicillin G procaine salt monohydrate Empirical Formula (Hill Notation): C 16 H 18 N 2 O 4 S 1 · C 13 H 20 N 2 O 2 · H 2 O Molecular Weight: 588.72

BENZYLPENICILLIN PROCAINE = PENICILLIN G PROCAINE ...

– Do not confu se procaine benzylpenicillin wit h short-acting benzylpenicillin (penicillin G), administered several times per day by IV route. – Do not mix with other drugs in the same syringe. – Storage: below 25 °C – Once reconstituted, suspension must be used immediately.

Penstrep-400 LA - Procaine & Benzathine penicillin ...

The combination of penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G and benzathine penicillin G are small-spectrum penicillins with a bactericidal action against mainly Gram-positive bacteria like Clostridium, Corynebacterium, Erysipelothrix, Listeria, penicillinase-negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an ...

Penicillin G for Chickens and Ducks - PoultryDVM

Penicillin G sodium and potassium powder for injection can be stored at room tempera­ture (15-30°C). After reconstituting, the injectable solution is stable for 7 days when kept refrigerated (2-8°C) and for 24 hours at room temperature. Penicillin G procaine should be stored at 2-8°C; avoid freezing.

CDC – Syphilis Treatment

Selection of the appropriate penicillin preparation is important to properly treat and cure syphilis. Combinations of some penicillin preparations (e.g., Bicillin C-R, a combination of benzathine penicillin and procaine penicillin) are not appropriate treatments for syphilis, as these combinations provide inadequate doses of penicillin.

Procaine penicillin G orally instead of a shot | BackYard ...

Aug 27, 2019 · Amoxicillin is even better than penicillin, IMO.-Kathy Just found this: "Chemically, the difference between amoxicillin and penicillin is the addition of an amino group to amoxicillin that makes it more polar and allows it to better penetrate gram-negative bacteria. Functionally, the difference is that amoxicillin is active against a broader spectrum of bacteria (not stronger against any of ...

What is the Right Dosage in Giving Penicillin to Cats ...

Since penicillin is a common antibiotic, it can be used both by humans and animals as long as there is no allergic reaction to this particular drug. Cats at home are very small in size compare to humans. In this case, the amount of the penicillin to be given must be smaller than the average dosage for humans.

Penicillin G Procaine - Manfaat, dosis dan efek samping ...

Apr 23, 2021 · Penicillin G procaine atau procaine benzylpenicillin adalah obat antibiotik untuk menangani infeksi bakteri, seperti anthrax, sifilis, atau infeksi Streptococcus beta-hemolitik grup A, atau infeksi Staphylococcus.. Penicillin G procaine bekerja dengan cara menghambat pembentukan dinding sel bakteri penyebab infeksi. Perlu diingat, obat ini tidak bisa infeksi akibat virus, seperti flu.

procaine penicillin | Michigan Medicine

Procaine penicillin is an antibiotic that fights bacteria in your body. Procaine penicillin is used to treat many different types of infections caused by bacteria, including syphilis (a sexually transmitted disease). Do not use this medication for any other infection that has not been checked by your doctor. Procaine...

Penicillin G Procaine Injectable Suspension (Routine ...

Each mL contains: penicillin g procaine 300,000 units, methylparaben 1.3mg, propylparaben0.2mg, sodium citrate 10mg, sodium carboxymethylcellulose 1mg, povidone 5mg, lecithin 6mg, sodium formaldehyde sulfoxylate 0.2mg, procaine hydrochloride 20mg, in Water for Injection q.s. Actions: Penicillin G is an effective bactericide in the treatment of ...

Penicillin G Procaine and Penicillin G Procaine for ...

» Penicillin G Procaine and Dihydrostreptomycinpreparation, on the basis of the labeled quantity in the por-Sulfate Injectable Suspension is a sterile suspen-tion of Injectable Suspension taken and the extent of dilu-tion, and the other terms are as defined therein.

REVIEW OF THE EFFICACY AND SAFETY OF PROCAINE ...

procaine penicillin. Sterile abscess formation with necrosis and sloughing of the injection site have been reported following IM injection of this formulation into both the thigh and buttocks. Quadriceps femoris fibrosis and atrophy have also been reported following repeated IM administration of procaine benzylpenicillin into the anterolateral ...

Penicillin G Benzathine And Penicillin G Procaine ...

Jun 23, 2020 · Penicillin G benzathine and penicillin G procaine is a combination slow-onset antibiotic that is used to treat many types of severe infections caused by bacteria, including strep infections ...

Penicillin Injectable - Durvet

Penicillin Injectable is a suspension of penicillin G procaine in 100, 250, and 500 mL multiple dose vials. Each mL is designed to provide 300,000 units of penicillin G as procaine in a stable suspension. Penicillin G procaine is an antibacterial agent which has activity against a variety of pathogenic organisms, mainly in the Gram-positive ...

DailyMed - BACTRACILLIN G- penicillin g procaine injection ...

May 26, 2021 · Bactracillin G is a suspension of penicillin G procaine in 100, 250, and 500 mL multiple dose vials. Each mL is designed to provide 300,000 units of penicillin G as procaine in a stable suspension. Penicillin G procaine is an antibacterial agent which has activity against a variety of pathogenic organisms, mainly in the Gram-positive category.

Benzylpenicillin benzathine 1.2 Million I.U. powder and ...

Nov 03, 2020 · Benzylpenicillin benzathine should not be used in tissues with reduced perfusion. Before initiating therapy with benzylpenicillin benzathine, a careful investigation should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins or other beta-lactam agents (see sections 4.3 and 4.8).

PenOne Pro (Penicillin G Procaine), 250 ml | Allivet

PenOne Pro (Penicillin G Procaine) is an injectable suspension indicated for the treatment of bacterial pneumonia (shipping fever) caused by Pasteurella multocida in cattle and sheep, erysipelas caused by Erysipelothrix insidiosa in swine, and strangles caused by Streptococcus equi in horses.

Penicillin [Equine] – OSU VMC Antimicrobial Use Guidelines

Brand Name(s) sodium penicillin G, potassium penicillin G, procaine penicillin G; penicillin V potassium. Background. Penicillin G is a bactericidal, time-dependent β-lactam antibiotic with good activity against many Gram-positive organisms, though it is not effective against β-lactamase-producing Staphylococcus spp., α-Streptococcus spp., or Rhodococcus equi.

Stability Studies of Penicillin Products, I, Procaine ...

Random samples of 10 ml, vials of procaine penicillin G in aqueous suspension were taken from each production batch and stored under various temperature conditions. For assays 0.5 ml, samples were withdrawn after thorough shaking and added to 200 ml, distilled water and mixed until solution was complete; or the sample was dissolved in 20 ml, 95 per cent. ethanol with subsequent dilution to 100...

gonorrhoea procaine penicillin plus probenecid*

excretion ofpenicillin. There is a dearth ofinformation regarding serum levels obtainedwiththelarger doses (1-2 mega-units and above) of procaine penicillin. The estimations by White et al. (1956) of the serum levels obtained during the 6 hr following the administration of 1-2 mega-units of procaine penicillin with and without 1 0gofprobenecid ...

China Procaine Price Powder, Procaine Price Powder ...

China Procaine Price Powder manufacturers - Select 2021 high quality Procaine Price Powder products in best price from certified Chinese Powder, Powder Package suppliers, wholesalers and factory on Made-in-China

BENZYLPENICILLIN, PROCAINE - uspbpep

Calculate the percentage contents of procaine and procaine benzylpenicillin. STORAGE In an airtight container. If the substance is sterile, store in a sterile, airtight, tamper-proof container. IMPURITIES A. 4-aminobenzoic acid, B. (4S)-2-[carboxy[(phenylacetyl)amino]methyl]-5,5-dimethylthiazolidine-4-carboxylic acid (penicilloic acids of ...

Can Dogs Take Penicillin - Everything You Need To Know ...

Sep 11, 2020 · Penicillin is commonly known as penicillin G, Pen G, or procaine penicillin. It is usually administered as an injectable (through the muscle or vein), oral tablet, or in liquid form as a syrup. Oral formulations are rarely prescribed and should be given on an empty stomach as food prevents the absorption of the drug through the gut.

Goat-Link - Penicillin G Procaine

Jan 14, 2010 · PENICILLIN G PROCAINE INJECTABLE SUSPENSION 300,000 Units per mL FOR ANIMAL USE ONLY DESCRIPTION: Penicillin G Procaine Injectable Suspension is available in 100-mL, 250-mL and 500-mL multiple-dose vials. Each mL contains: penicillin G procaine 300,000 units, methylparaben 1.3 mg, propylparaben 0.2 mg, sodium citrate 10 mg, sodium carboxymethylcellulose …

Penicillin G Benzathine & Procaine Injection l Injectable ...

Package Information: Penicillin G Benzathine and Penicillin G Procaine is available in vials of 100 mL and 250 mL with each mL containing 150,000 units penicillin G benzathine and 150,000 units penicillin G procaine. Penicillin G Benzathine and Penicillin G Procaine should be stored under refrigeration 2°-8°C (36°-46°F). Avoid freezing.

Procaine Benzylpenicillin - an overview | ScienceDirect Topics

Procaine penicillin G is a combination of benzylpenicillin with the local anaesthetic agent procaine. It is slowly absorbed after IM administration and hydrolysed to benzylpenicillin and thus used to achieve prolonged but low concentrations of benzylpenicillin. The combination seeks to reduce the pain and discomfort associated with a large IM ...

BASHH Guidelines

Procaine penicillin G 600,000 units IM OD for 14 days: 1C. Amoxycillin 2g PO t.d.s. plus probenecid 500mg q.d.s for 28 days: 2C (b) Neurosyphilis in pregnancy. Procaine penicillin G 1.8–2.4 MU IM o.d. plus pro-benecid 500mg PO q.d.s. for 14 days: 1C 2010. Benzylpenicillin 10.8–14.4g daily, given as 1.8–2.4g IV every 4h for 14 days: 1C.

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